Panic Coda

Web: panic.com/coda | License: Commercial, $99

All the coding tools you could need in one place, including syntax-highlighted editing of all major code-types such as PHP, CSS, HTML, Ruby, Javascript, XML and more. I particularly love the excellent Site Manager which stores all of your sites in one place and provide easy access for direct, live editing of the site code using FTP, and the clips manager that serves as a snippets repository for reusable code.

Filezilla

Web: filezilla-project.org | License: Free

Simple to use and packed with great features – one of the best free FTP clients out there.

Adobe Fireworks

Web: www.adobe.com/products/fireworks | License: Commercial, ~$299

Easy to use graphics editor with the best support for PNGs for web use. Build rapid designs and slice them up ready to build into a template. Fireworks can also handle (most) Photoshop PSDs with ease, so it's particularly useful if you work with designers who prefer to work in Photoshop.

VMware Fusion

Web: www.vmware.com/products/fusion | License: Commercial, $79.99

Set-up multiple operating systems which can be run in OS X without needing to reboot. Essential for effective cross-browser testing.

MAMP

Web: www.mamp.info | License: Free (Pro version: £39)

Localhost server environment to enable fast, live development – provides a one-click server running Apache, PHP and MySQL.

Quicksilver

Web: docs.blacktree.com/quicksilver/quicksilver | License: Free

Quickly access all of your applications at the touch of a button – no more searching around in your Apps folder!

Apple Time Machine

Web: www.apple.com/macosx/what-is-macosx/time-machine.html | License: Free (ships with Mac OS X)

The perfect incremental backup solution – and best of all, ships with OS X and is seamlessly integrated. Just add an external disk drive!

Betterzip

Web: macitbetter.com | License: Shareware, $19.95

Brilliant archive utility offering a variety of formats and and easy-to-use interface.

Skype

Web: www.skype.com | License: Free

Communicate with worldwide clients for free, or add a real phone number without needing a physical phone line.

Process

Web: www.jumsoft.com/process | License: Shareware, $39

Useful task-list and project tracking.